/* Prime Peptide Primer — large letters, broad paint, open pages. */
:root{--primer-ground:#EFF9EC;--primer-ink:#2E2F22;--primer-violet:#4B237B;--primer-blue:#C5CCE2;--primer-paper:#FBFCFA;--primer-measure:1280px;font-family:Mulish,"Trebuchet MS",sans-serif;color:var(--primer-ink);background:var(--primer-ground);font-synthesis:none;scroll-behavior:smooth}
*{box-sizing:border-box}body{margin:0}img{display:block;max-width:100%;height:auto}a{color:var(--primer-violet);text-decoration-thickness:1.5px;text-underline-offset:4px;transition:color .18s,background-color .18s,box-shadow .18s,transform .18s}a:hover{text-decoration-thickness:3px}a:focus-visible{outline:3px solid var(--primer-violet);outline-offset:5px}::selection{background:var(--primer-blue);color:var(--primer-ink)}p,li{font-size:18px;line-height:1.7}p{margin:0 0 1.1em}h1,h2,h3{margin:0;font-weight:400}h1,h2,.ppp-initial,.ppp-nav-letter,.ppp-photo-word{font-family:"Bowlby One","Arial Black",sans-serif}h1{font-size:clamp(36px,4vw,58px);line-height:1.15;letter-spacing:-.025em}h2{font-size:clamp(28px,3.1vw,44px);line-height:1.2;letter-spacing:-.02em}h3{font-size:22px;font-weight:800;line-height:1.4}section[id],aside[id]{scroll-margin-top:28px}.ppp-wrap{width:min(var(--primer-measure),calc(100% - 160px));margin-inline:auto}.ppp-skip{position:absolute;z-index:10;left:16px;top:0;padding:12px;background:var(--primer-paper);transform:translateY(-150%)}.ppp-skip:focus{transform:translateY(8px)}.ppp-icon{display:inline-block;width:22px;height:22px;stroke-width:1.7;flex:none;vertical-align:middle}
/* Five anchors are the wordmark. */
.ppp-masthead{position:relative;z-index:1;padding:12px 0 13px;background:var(--primer-ground)}.ppp-prime-nav{display:grid;grid-template-columns:repeat(5,minmax(0,1fr));column-gap:24px}.ppp-prime-nav a{display:flex;flex-direction:column;align-items:flex-start;color:var(--primer-ink);text-decoration:none}.ppp-nav-letter{font-size:72px;line-height:.95;color:var(--primer-violet);transition:transform .18s ease}.ppp-nav-label{display:flex;align-items:center;gap:14px;font-size:16px;line-height:1.2;font-weight:700;margin-top:7px}.ppp-nav-label .ppp-icon{width:18px;height:18px}.ppp-prime-nav a:hover .ppp-nav-letter{transform:translate(6px,-3px)}.ppp-prime-nav a:hover .ppp-nav-label{text-decoration:underline;text-underline-offset:4px}.ppp-signature{display:block;width:fit-content;margin:6px 0 0 auto;color:var(--primer-ink);font-size:13px;line-height:1.2;text-decoration:none}.ppp-signature:hover{text-decoration:underline}
/* The photograph remains open at the right; all words sit on opaque grounds. */
.ppp-opening{position:relative;isolation:isolate;background:var(--primer-ground);padding:38px 0 42px}.ppp-hero-scene{position:absolute;inset:0;z-index:-2;width:100%;height:100%;object-fit:cover;object-position:center 52%}.ppp-opening::before{content:"";position:absolute;inset:0 auto 0 0;width:calc(50% + 28px);z-index:-1;background:var(--primer-ground)}.ppp-home-composition{display:grid;grid-template-columns:minmax(0,1.06fr) minmax(0,.94fr);grid-template-areas:"headline picture" "welcome picture" "book book";column-gap:32px}.ppp-headline{grid-area:headline;background:var(--primer-ground);padding:6px 30px 0 0}.ppp-headline h1{font-size:clamp(38px,3.7vw,54px);max-width:620px}.ppp-welcome-run{grid-area:welcome;display:grid;grid-template-columns:118px minmax(0,1fr);gap:22px;padding:30px 30px 22px 0;min-height:180px;background:var(--primer-ground)}.ppp-welcome-copy>p{font-size:18px;line-height:1.6;margin:0;max-width:460px}.ppp-initial{display:block;position:relative;isolation:isolate;align-self:start;color:var(--primer-violet);font-size:260px;line-height:.85;letter-spacing:-.06em;margin-left:-8px}.ppp-initial::before{content:"";position:absolute;z-index:-1;background:var(--primer-blue);width:66%;height:22%;left:21%;bottom:-8px}.ppp-welcome-run>.ppp-initial{font-size:142px}.ppp-photo-mark{grid-area:picture;position:relative;align-self:end;height:132px;margin:0 0 24px -35px;padding:20px 12px;background:var(--primer-paper);transform:rotate(-3deg);box-shadow:12px 12px 0 var(--primer-blue);isolation:isolate}.ppp-photo-word{display:block;font-size:clamp(58px,7vw,110px);line-height:.9;letter-spacing:.045em;text-align:center;white-space:nowrap;color:var(--primer-violet);background-color:var(--primer-violet);background-image:url("./shed-prime.webp");background-size:cover;background-position:center 40%;background-clip:text;-webkit-background-clip:text;-webkit-text-fill-color:transparent;user-select:none}.ppp-roller-pop{position:absolute;right:3%;top:-16px;width:68px;height:68px;background:var(--primer-blue) url("./shed-prime.webp") 85% 29%/730% auto;animation:ppp-settle .65s ease-out both}
/* An open spread, with no interaction or card effects. */
.ppp-book{grid-area:book;display:grid;grid-template-columns:1fr 1fr;gap:24px;background:var(--primer-ground);margin-top:28px}.ppp-book-page{padding:21px 28px 23px;background:var(--primer-blue);font-size:16px;line-height:1.5;margin:0;color:var(--primer-ink)}.ppp-book-page+.ppp-book-page{background:#DCE1ED}.ppp-book-heading{display:block;font-size:16px;font-weight:800;line-height:1.3;margin-bottom:8px}
/* Unequal full-width reading runs, rather than a row of cards. */
.ppp-home-primer{padding-top:70px}.ppp-first-explanation{display:grid;grid-template-columns:.88fr 1.12fr;gap:75px;padding:0 0 70px}.ppp-first-explanation h2{max-width:450px}.ppp-first-explanation p{max-width:660px}.ppp-first-explanation p:last-child{margin-bottom:0}.ppp-reading-run{padding:88px 0;position:relative}.ppp-run-grid{display:grid;grid-template-columns:300px minmax(0,1fr);gap:68px}.ppp-run-marker{position:sticky;top:32px;align-self:start}.ppp-run-body{max-width:850px}.ppp-run-body h2{position:relative;max-width:830px;margin-bottom:28px}.ppp-run-body h2>.ppp-icon{display:block;margin-bottom:16px;width:32px;height:32px}.ppp-run-prose{max-width:720px}.ppp-repair-run{background:var(--primer-paper);padding-top:100px;padding-bottom:100px}.ppp-repair-run .ppp-run-grid{grid-template-columns:360px minmax(0,1fr);gap:65px}.ppp-repair-run .ppp-initial{font-size:340px;margin-top:-36px}.ppp-repair-run .ppp-run-marker::after{content:"";display:block;position:relative;width:340px;height:190px;margin:-30px 0 0 12px;background:var(--primer-blue) url("./copper-light.webp") center/cover;box-shadow:-18px 18px 0 var(--primer-blue);transform:rotate(-3deg)}.ppp-context-run{background:var(--primer-blue);padding:90px 0 110px}.ppp-context-run .ppp-run-grid{grid-template-columns:170px minmax(0,1fr);gap:95px}.ppp-context-run .ppp-initial::before{background:var(--primer-ground)}.ppp-context-run .ppp-run-body{max-width:900px}.ppp-linked-reads{display:flex;flex-wrap:wrap;gap:12px 28px;margin-top:30px}.ppp-reading-link{display:inline-flex;align-items:center;gap:10px;font-weight:800;margin:4px 0 10px;padding-bottom:5px}.ppp-linked-reads .ppp-reading-link{padding:15px 18px;background:var(--primer-paper);box-shadow:5px 5px 0 var(--primer-violet);text-decoration:none}.ppp-linked-reads .ppp-reading-link:nth-child(2){transform:translateY(13px)}.ppp-linked-reads .ppp-reading-link:hover,.ppp-linked-reads .ppp-reading-link:focus-visible{transform:translate(-3px,-3px);box-shadow:8px 8px 0 var(--primer-violet)}.ppp-long-thought{background:var(--primer-violet);color:var(--primer-paper);padding:76px 0 80px;position:relative}.ppp-long-thought .ppp-wrap{position:relative}.ppp-long-thought h2{font-size:clamp(36px,5.2vw,74px);max-width:1050px;line-height:1.13}.ppp-long-thought p{font-size:22px;line-height:1.6;max-width:700px;margin:34px 0 0 auto}.ppp-long-thought .ppp-icon{position:absolute;width:100px;height:100px;right:0;top:-115px;padding:17px;color:var(--primer-violet);background:var(--primer-ground);box-shadow:9px 9px 0 var(--primer-blue);transform:rotate(6deg)}.ppp-question-run{padding:100px 0 84px}.ppp-question-run .ppp-run-grid{grid-template-columns:340px minmax(0,1fr);gap:36px}.ppp-question-run .ppp-initial{margin-left:-32px;font-size:300px}.ppp-question-run .ppp-run-prose p:first-child{font-size:23px;line-height:1.55}.ppp-evidence-run{background:var(--primer-paper);padding:85px 0 110px}.ppp-evidence-run .ppp-run-grid{grid-template-columns:230px minmax(0,1fr);gap:100px}.ppp-evidence-run .ppp-initial{font-size:220px}.ppp-evidence-run .ppp-run-prose{columns:2;column-gap:38px;max-width:860px}.ppp-evidence-run .ppp-run-prose p{break-inside:avoid}
/* Inner-page photographs are bands with a caption slipped over the lower edge. */
.ppp-guide-cover{padding:35px 0 48px;background:var(--primer-ground)}.ppp-breadcrumb{font-size:16px;margin-bottom:32px;line-height:1.5}.ppp-cover-grid{display:grid;grid-template-columns:210px minmax(0,1fr);gap:44px}.ppp-cover-grid>.ppp-initial{font-size:220px}.ppp-cover-grid h1{max-width:970px}.ppp-cover-intro{font-size:21px;max-width:810px;line-height:1.65;margin:24px 0 0}.ppp-cover-photo{margin:0 0 38px;position:relative;background:var(--primer-blue)}.ppp-cover-photo img{width:100%;height:300px;object-fit:cover;object-position:center 52%;background:var(--primer-blue)}.ppp-cover-photo figcaption{position:relative;max-width:510px;margin:-37px 80px -28px auto;padding:20px 24px;font-size:16px;line-height:1.5;background:var(--primer-paper);box-shadow:10px 10px 0 var(--primer-blue)}.ppp-guide-reading{padding:28px 0 85px}.ppp-guide-section{display:grid;grid-template-columns:310px minmax(0,1fr);gap:75px;padding:45px 0 50px;border-top:4px solid var(--primer-blue)}.ppp-guide-section h2{position:sticky;top:28px;align-self:start;font-size:30px;max-width:310px}.ppp-guide-section h2>.ppp-icon{display:block;width:30px;height:30px;margin-bottom:16px}.ppp-guide-prose{max-width:770px}.ppp-guide-prose p:last-child{margin-bottom:0}.ppp-guide-section:nth-child(2) .ppp-guide-prose>p:first-child{position:relative;padding:26px 30px;margin-left:-30px;margin-bottom:30px;background:var(--primer-blue);box-shadow:10px 10px 0 var(--primer-ground);font-size:21px;line-height:1.6}.ppp-facts-table{border-collapse:collapse;width:100%;margin:28px 0 32px;background:var(--primer-paper)}.ppp-facts-table caption{text-align:left;font-size:18px;font-weight:800;margin-bottom:15px}.ppp-facts-table th,.ppp-facts-table td{text-align:left;vertical-align:top;padding:18px;border-bottom:4px solid var(--primer-ground);font-size:17px;line-height:1.6}.ppp-facts-table thead{background:var(--primer-blue)}.ppp-facts-table tbody th{color:var(--primer-violet);font-weight:800;width:19%}.ppp-source-entry{padding:25px 0;border-bottom:2px solid var(--primer-blue)}.ppp-source-entry:first-child{padding-top:0}.ppp-source-entry h3{font-size:19px;margin-bottom:9px}.ppp-source-entry p{font-size:17px;margin:0;line-height:1.6}.ppp-next-read{display:flex;gap:16px;align-items:center;padding:26px 30px;background:var(--primer-blue);margin:25px 0 0 385px;box-shadow:8px 8px 0 var(--primer-violet);font-size:18px;font-weight:800;text-decoration:none}.ppp-next-read:hover,.ppp-next-read:focus-visible{background:var(--primer-paper);transform:translate(-3px,-3px);box-shadow:11px 11px 0 var(--primer-violet)}
.ppp-footer{padding:55px 0 28px;background:var(--primer-blue)}.ppp-footer-top{display:grid;grid-template-columns:1fr 1fr;gap:70px}.ppp-footer-title{font-family:"Bowlby One","Arial Black",sans-serif;font-size:34px;max-width:440px;line-height:1.25;color:var(--primer-violet)}.ppp-footer-sentence{font-size:16px;line-height:1.65;max-width:430px;margin-top:20px}.ppp-footer-links{display:grid;grid-template-columns:1fr 1fr;gap:18px 25px;align-content:start}.ppp-footer-links a{font-size:16px;font-weight:700;width:fit-content}.ppp-copyright{font-size:14px;margin:38px 0 0}.ppp-404{min-height:60vh;padding:65px 0 100px}.ppp-404 h1{max-width:900px}.ppp-404 p{max-width:700px;margin:25px 0}
@keyframes ppp-settle{from{transform:translateY(9px)}to{transform:translateY(0)}}
@media(max-width:1100px){.ppp-wrap{width:calc(100% - 80px)}.ppp-nav-letter{font-size:58px}.ppp-nav-label{gap:8px}.ppp-home-composition{grid-template-columns:minmax(0,1.12fr) minmax(0,.88fr);column-gap:20px}.ppp-opening::before{width:56%}.ppp-welcome-run{grid-template-columns:85px minmax(0,1fr);gap:14px;padding-right:10px}.ppp-welcome-run>.ppp-initial{font-size:105px}.ppp-headline{padding-right:10px}.ppp-photo-mark{height:110px;margin-left:-12px;padding-top:25px}.ppp-photo-word{font-size:6.8vw}.ppp-first-explanation{gap:40px}.ppp-run-grid,.ppp-repair-run .ppp-run-grid{grid-template-columns:250px minmax(0,1fr);gap:40px}.ppp-repair-run .ppp-initial{font-size:280px}.ppp-repair-run .ppp-run-marker::after{width:225px;height:165px}.ppp-context-run .ppp-run-grid{grid-template-columns:150px minmax(0,1fr);gap:45px}.ppp-question-run .ppp-run-grid{grid-template-columns:230px minmax(0,1fr);gap:40px}.ppp-question-run .ppp-initial{font-size:245px;margin-left:-15px}.ppp-evidence-run .ppp-run-grid{grid-template-columns:190px minmax(0,1fr);gap:50px}.ppp-evidence-run .ppp-run-prose{columns:auto}.ppp-cover-grid{grid-template-columns:160px minmax(0,1fr);gap:30px}.ppp-cover-grid>.ppp-initial{font-size:175px}.ppp-cover-photo figcaption{margin-right:40px}.ppp-guide-section{grid-template-columns:240px minmax(0,1fr);gap:45px}.ppp-guide-section h2{font-size:27px}.ppp-next-read{margin-left:285px}}
@media(max-width:700px){:root{scroll-behavior:auto}.ppp-wrap{width:calc(100% - 36px)}p,li{font-size:17px;line-height:1.65}.ppp-masthead{padding:6px 0 5px}.ppp-prime-nav{gap:3px}.ppp-nav-letter{font-size:26px;line-height:1.1}.ppp-nav-label{display:block;font-size:16px;line-height:1.05;font-weight:600;max-width:100%;margin-top:3px;letter-spacing:-.025em}.ppp-nav-label .ppp-icon{display:none}.ppp-signature{font-size:11px;line-height:1.2;margin-top:4px}.ppp-opening{display:flex;flex-direction:column;padding:20px 0 0}.ppp-opening::before{display:none}.ppp-home-composition{order:0;grid-template-columns:minmax(0,1fr);grid-template-areas:"headline" "welcome" "book" "picture";gap:0}.ppp-headline{padding:0}.ppp-headline h1{font-size:27px;line-height:1.16;letter-spacing:-.02em}.ppp-welcome-run{grid-template-columns:64px minmax(0,1fr);gap:14px;padding:20px 0 0;min-height:0}.ppp-initial,.ppp-welcome-run>.ppp-initial{font-size:64px;line-height:.92;letter-spacing:-.06em;margin:0}.ppp-initial::before{height:17px;bottom:-6px;left:15px;width:44px}.ppp-welcome-copy>p{font-size:16px;line-height:1.45;margin:0}.ppp-book{grid-template-columns:1fr;gap:0;margin-top:20px}.ppp-book-page{font-size:16px;line-height:1.4;padding:13px 15px 14px}.ppp-book-page+.ppp-book-page{border-top:6px solid var(--primer-ground)}.ppp-book-heading{font-size:16px;line-height:1.2;margin-bottom:5px}.ppp-photo-mark{height:80px;margin:25px 0 20px;padding:8px 0 0;transform:rotate(-2deg);box-shadow:7px 7px 0 var(--primer-blue)}.ppp-photo-word{font-size:70px;line-height:.9;letter-spacing:.045em;height:80px}.ppp-roller-pop{width:33px;height:34px;right:4%;top:-16px}.ppp-hero-scene{position:static;order:1;width:100%;height:205px;object-fit:cover;object-position:center 56%;z-index:auto}.ppp-home-primer{padding-top:36px}.ppp-first-explanation{display:block;padding:0 0 38px}.ppp-first-explanation h2{font-size:27px;margin-bottom:20px}.ppp-reading-run,.ppp-repair-run,.ppp-context-run,.ppp-question-run,.ppp-evidence-run{padding:40px 0}.ppp-run-grid,.ppp-repair-run .ppp-run-grid,.ppp-context-run .ppp-run-grid,.ppp-question-run .ppp-run-grid,.ppp-evidence-run .ppp-run-grid{display:grid;grid-template-columns:64px minmax(0,1fr);gap:0 14px}.ppp-run-marker{display:contents}.ppp-run-marker>.ppp-initial,.ppp-repair-run .ppp-initial,.ppp-question-run .ppp-initial,.ppp-evidence-run .ppp-initial{font-size:64px;grid-column:1;grid-row:2;margin:4px 0 0;width:64px}.ppp-run-body{display:contents}.ppp-run-body h2{grid-column:1/-1;grid-row:1;font-size:27px;margin-bottom:20px}.ppp-run-body h2>.ppp-icon{width:27px;height:27px;margin-bottom:13px}.ppp-run-prose{display:contents!important}.ppp-run-prose p,.ppp-question-run .ppp-run-prose p:first-child{grid-column:1/-1;font-size:17px;line-height:1.65}.ppp-run-prose p:first-child{grid-column:2;grid-row:2}.ppp-repair-run .ppp-run-marker::after{display:block;grid-column:1/-1;width:calc(100% - 12px);height:170px;margin:5px 0 20px 12px;transform:rotate(-2deg);box-shadow:-10px 10px 0 var(--primer-blue)}.ppp-linked-reads{grid-column:1/-1;gap:10px;margin-top:12px;padding-bottom:15px}.ppp-linked-reads .ppp-reading-link{font-size:16px;padding:12px;gap:8px;margin-bottom:8px;box-shadow:4px 4px 0 var(--primer-violet)}.ppp-linked-reads .ppp-reading-link:nth-child(2){transform:none}.ppp-long-thought{padding:45px 0 38px}.ppp-long-thought h2{font-size:32px}.ppp-long-thought p{font-size:18px;margin:24px 0 0 25px}.ppp-long-thought .ppp-icon{top:-72px;right:4px;width:57px;height:57px;padding:10px;box-shadow:5px 5px 0 var(--primer-blue)}.ppp-guide-cover{padding:23px 0 32px}.ppp-breadcrumb{font-size:16px;margin-bottom:25px}.ppp-cover-grid{grid-template-columns:64px minmax(0,1fr);gap:20px 14px}.ppp-cover-grid>div{display:contents}.ppp-cover-grid>.ppp-initial{font-size:64px;grid-column:1;grid-row:2;margin:4px 0 0;width:64px}.ppp-cover-grid h1{grid-column:1/-1;grid-row:1;font-size:30px;line-height:1.2}.ppp-cover-intro{grid-column:2;grid-row:2;font-size:18px;line-height:1.6;margin:0}.ppp-cover-photo{margin-bottom:30px}.ppp-cover-photo img{height:195px}.ppp-cover-photo figcaption{font-size:16px;padding:15px 18px;max-width:none;margin:-25px 18px 0 36px;box-shadow:6px 6px 0 var(--primer-blue)}.ppp-guide-reading{padding:15px 0 48px}.ppp-guide-section{display:block;padding:28px 0 32px}.ppp-guide-section h2{position:static;font-size:26px;max-width:none;margin-bottom:21px}.ppp-guide-section h2>.ppp-icon{width:26px;height:26px;margin-bottom:12px}.ppp-guide-section:nth-child(2) .ppp-guide-prose>p:first-child{font-size:19px;margin-left:-9px;padding:20px 22px;box-shadow:7px 7px 0 var(--primer-paper)}.ppp-facts-table{margin-top:22px}.ppp-facts-table thead{display:none}.ppp-facts-table tbody tr{display:block;padding:12px 16px;border-bottom:6px solid var(--primer-ground)}.ppp-facts-table tbody th,.ppp-facts-table td{display:block;width:100%;padding:7px 0;border:0;font-size:17px}.ppp-table-key{display:block;font-weight:800;color:var(--primer-ink)}.ppp-next-read{margin:12px 7px 0 0;padding:22px 20px;box-shadow:6px 6px 0 var(--primer-violet)}.ppp-footer{padding:36px 0 24px}.ppp-footer-top{grid-template-columns:1fr;gap:28px}.ppp-footer-title{font-size:27px}.ppp-footer-sentence{font-size:16px}.ppp-footer-links{gap:17px 20px}.ppp-copyright{margin-top:29px}.ppp-404{padding:40px 0 65px}.ppp-404 h1{font-size:30px}}
@media(min-width:701px){.ppp-table-key{display:none}}
@media(prefers-reduced-motion:reduce){:root{scroll-behavior:auto}*,*::before,*::after{animation:none!important;transition:none!important}}